5-AMINOPYRROLO[3,2-B]PYRIDINE
1H-pyrrolo[3,2-b]pyridin-5-amine
CAS: 131084-54-3;207849-66-9
Molecular Formula: C7H7N3
5-AMINOPYRROLO[3,2-B]PYRIDINE - Names and Identifiers
| Name | 1H-pyrrolo[3,2-b]pyridin-5-amine |
| Synonyms | 5-Amino-4-azaindole 5-AMino-4-Azaindole HCl 5-AMINOPYRROLO[3,2-B]PYRIDINE 1H-pyrrolo3,2-bpyridin-5-amine 1H-pyrrolo[3,2-b]pyridin-5-amine 5-AMino-4-azaindole hydrochloride 1H-Pyrrolo[3,2-b]pyridin-5-ylamine 1H-pyrrolo[3,2-b]pyridin-5-aMine HCl 1H-Pyrrolo[3,2-b]pyridin-5-amine(9CI) |
| CAS | 131084-54-3 207849-66-9 |
| InChI | InChI=1/C7H7N3/c8-7-2-1-5-6(10-7)3-4-9-5/h1-4,9H,(H2,8,10) |
5-AMINOPYRROLO[3,2-B]PYRIDINE - Physico-chemical Properties
| Molecular Formula | C7H7N3 |
| Molar Mass | 133.15 |
| Density | 1.367 |
| Boling Point | 354.7±22.0 °C(Predicted) |
| Flash Point | 195.469°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 15.05±0.40(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.78 |
5-AMINOPYRROLO[3,2-B]PYRIDINE - Introduction
5-Amino-4-azaindole (5-Amino-4-nitroimidazole) is an organic compound containing amino and nitro functional groups. Its chemical formula is C3H3N5O2.
The compound has the following properties:
1. appearance: 5-amino -4-azaindole is yellow crystal or powder solid.
2. Melting point: Its melting point is 158-161 degrees Celsius.
3. Solubility: Almost insoluble in water, but soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide.
Use:
5-Amino-4-azaindole is often used as an intermediate in organic synthesis and plays an important role in the preparation of other compounds. It also has some applications in the medical field, such as the synthesis of certain antibacterial and antiparasitic drugs.
Preparation Method:
In general, 5-amino -4-azaindole can be prepared by a nitration reaction. One method is to react 2-acetamido-4-cyclohexenone with sodium nitroprusside in a carbonate buffer solution to produce the desired product.
Safety Information:
Limited safety information on 5-amino-4-azaindole. It can be potentially dangerous and should be handled and stored with caution. During use, it is recommended to wear appropriate personal protective equipment, such as laboratory gloves and goggles, to ensure safe operation. In order to prevent the exhaust bucket from overflowing, it is necessary to operate in a well-ventilated area. If accidental events such as inhalation, ingestion or skin contact occur, seek medical attention immediately.
Please note that when using chemicals, correct laboratory practices must be followed and appropriate protective measures must be used to ensure personal and environmental safety.
The compound has the following properties:
1. appearance: 5-amino -4-azaindole is yellow crystal or powder solid.
2. Melting point: Its melting point is 158-161 degrees Celsius.
3. Solubility: Almost insoluble in water, but soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide.
Use:
5-Amino-4-azaindole is often used as an intermediate in organic synthesis and plays an important role in the preparation of other compounds. It also has some applications in the medical field, such as the synthesis of certain antibacterial and antiparasitic drugs.
Preparation Method:
In general, 5-amino -4-azaindole can be prepared by a nitration reaction. One method is to react 2-acetamido-4-cyclohexenone with sodium nitroprusside in a carbonate buffer solution to produce the desired product.
Safety Information:
Limited safety information on 5-amino-4-azaindole. It can be potentially dangerous and should be handled and stored with caution. During use, it is recommended to wear appropriate personal protective equipment, such as laboratory gloves and goggles, to ensure safe operation. In order to prevent the exhaust bucket from overflowing, it is necessary to operate in a well-ventilated area. If accidental events such as inhalation, ingestion or skin contact occur, seek medical attention immediately.
Please note that when using chemicals, correct laboratory practices must be followed and appropriate protective measures must be used to ensure personal and environmental safety.
Last Update：2024-04-09 21:54:55
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